Products
Online Inquiry
Calcium-dependent protein kinase 6 (CPK6), Recombinant Protein
Cat: RP01529
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana Calcium-dependent protein kinase 6 (CPK6) , partial
Product Gene Name
CPK6 recombinant protein
Product Synonym Gene Name
CPK6
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
61,111 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Calcium-dependent protein kinase
NCBI/Uniprot Data
NCBI Accession #
NP_001324056.1
NCBI GI #
1063703992
NCBI GenBank Nucleotide #
NM_001335545.1
NCBI GeneID
816235
NCBI Official Full Name
Calcium-dependent protein kinase family protein
NCBI Official Symbol
CPK6
NCBI Official Synonym Symbols
ARABIDOPSIS THALIANA CALCIUM-DEPENDENT PROTEIN KINASE 6; ARABIDOPSIS THALIANA CALMODULIN-DOMAIN PROTEIN KINASE 3; ATCDPK3; ATCPK6; calcium dependent protein kinase 6; CALCIUM-DEPENDENT PROTEIN KINASE 6; CALMODULIN-DOMAIN PROTEIN KINASE 3; F5J6.13; F5J6_13
NCBI Protein Information
Calcium-dependent protein kinase family protein
NCBI Summary
Encodes calcium dependent protein kinase 6 (CPK6), a member of the Arabidopsis CDPK gene family. CDPKs contain an intrinsic Ca2+-activation domain with four EF hand Ca2+-binding sites. CDPKs protein kinases have been proposed to function in multiple plant signal transduction pathways downstream of [Ca2+]cyt elevations, thus transducing various physiological responses. CPK6 is expressed in both guard cells and mesophyll cells. Functions in guard cell ion channel regulation. ABA and Ca(2+) activation of slow-type anion channels and, interestingly, ABA activation of plasma membrane Ca(2+)-permeable channels were impaired in independent alleles of single and double cpk3cpk6 mutant guard cells. Furthermore, ABA- and Ca(2+)-induced stomatal closing were partially impaired in these cpk3cpk6 mutant alleles. The protein kinase CPK6 is shown in biochemical assays to be directly activated by elevations in calcium concentrations in the physiological range (Laanements et al., 2013 PlantPhys.; PMID: 23766366). These data correlate with the in vivo function of CPK6 in Ca2+ and ABA activation of S-type anion channels (Mori et al., 2006 PLoS Biol.; PMID: 17032064) and the ability of CPK6 to mediate ABA activation of SLAC1 (Brandt et al., 2012 PNAS; PMID: 22689970).
UniProt Gene Name
CPK6
UniProt Synonym Gene Names
CDPK3; AtCDPK3
UniProt Protein Name
Calcium-dependent protein kinase 6
UniProt Synonym Protein Names
Calcium-dependent protein kinase isoform CDPK3; AtCDPK3; Calmodulin-domain protein kinase CDPK isoform 6
UniProt Primary Accession #
Q38872
UniProt Secondary Accession #
Q39014
UniProt Related Accession #
Q38872
UniProt Comments
May play a role in signal transduction pathways that involve calcium as a second messenger. Functions in abscisic acid (ABA) regulation of guard cell S-type anion-and Ca2+-permeable channels and stomatal closure (PubMed:17032064). Phosphorylates FD (PubMed:25661797).
For research use only, not for clinical use.