NCBI Accession #
NP_194096.1
NCBI GenBank Nucleotide #
NM_118496.4
NCBI Official Full Name
calcium-dependent protein kinase 6
NCBI Official Symbol
CDPK6
NCBI Official Synonym Symbols
AtCDPK6; Calcium dependent protein kinase 3; calcium-dependent protein kinase 6; CALCIUM-DEPENDENT PROTEIN KINASE 6; CPK3; F9D16.120; F9D16_120
NCBI Protein Information
calcium-dependent protein kinase 6
NCBI Summary
Encodes calcium dependent protein kinase 3 (CPK3), a member of the Arabidopsis CDPK gene family. CDPKs contain an intrinsic Ca2+-activation domain with four EF hand Ca2+-binding sites. CDPKs protein kinases have been proposed to function in multiple plant signal transduction pathways downstream of [Ca2+]cyt elevations, thus transducing various physiological responses. CPK3 is expressed in both guard cells and mesophyll cells. Functions in guard cell ion channel regulation. ABA and Ca(2+) activation of slow-type anion channels and, interestingly, ABA activation of plasma membrane Ca(2+)-permeable channels were impaired in independent alleles of single and double cpk3cpk6 mutant guard cells. Furthermore, ABA- and Ca(2+)-induced stomatal closing were partially impaired in these cpk3cpk6 mutant alleles. CPK6 is also a member of the Arabidopsis CDPK family.
UniProt Synonym Gene Names
CDPK6; AtCDPK6
UniProt Protein Name
Calcium-dependent protein kinase 3
UniProt Synonym Protein Names
Calcium-dependent protein kinase isoform CDPK6; AtCDPK6
UniProt Primary Accession #
Q42479
UniProt Secondary Accession #
Q941A2
UniProt Related Accession #
Q42479
UniProt Comments
May play a role in signal transduction pathways that involve calcium as a second messenger. Functions in abscisic acid (ABA) regulation of guard cell S-type anion-and Ca2+-permeable channels and stomatal closure.