Calcineurin B-like protein 4 (CBL4), Recombinant Protein
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Calcineurin B-like protein 4 (CBL4), Recombinant Protein

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Cat: RP01357
Size: 0.02 mg (E-Coli)/ 0.1 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 1 mg (E-Coli)/ 0.1 mg (Baculovirus)/ 1 mg (Yeast)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana Calcineurin B-like protein 4 (CBL4)
Product Gene Name
CBL4 recombinant protein
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
GCSVSKKKKK NAMRPPGYED PELLASVTPF TVEEVEALYE LFKKLSSSII DDGLIHKEEF QLALFRNRNR RNLFADRIFD VFDVKRNGVI EFGEFVRSLG VFHPSAPVHE KVKFAFKLYD LRQTGFIERE ELKEMVVALL HESELVLSED MIEVMVDKAF VQADRKNDGK IDIDEWKDFV SLNPSLIKNM TLPYLKDINR TFPSFVSSCE EEEMELQNVS S
Sequence Positions
2-222, Full length protein
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
25,693 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Calcineurin B-like protein

NCBI/Uniprot Data

NCBI Accession #
NP_001190377.1
NCBI GI #
334187892
NCBI GenBank Nucleotide #
NM_001203448.2
NCBI GeneID
832494
NCBI Official Full Name
Calcium-binding EF-hand family protein
NCBI Official Symbol
SOS3
NCBI Official Synonym Symbols
ATSOS3; CALCINEURIN B-LIKE PROTEIN 4; CBL4; MOP9.19; MOP9_19; SALT OVERLY SENSITIVE 3
NCBI Protein Information
Calcium-binding EF-hand family protein
NCBI Summary
encodes a calcium sensor that is essential for K+ nutrition, K+/Na+ selectivity, and salt tolerance. The protein is similar to calcineurin B. Lines carrying recessive mutations are hypersensitive to Na+ and Li+ stresses and is unable to grow in low K+. The growth defect is rescued by extracellular calcium.
UniProt Gene Name
CBL4
UniProt Synonym Gene Names
SOS3
UniProt Protein Name
Calcineurin B-like protein 4
UniProt Synonym Protein Names
Protein SALT OVERLY SENSITIVE 3
UniProt Primary Accession #
O81223
UniProt Related Accession #
O81223
UniProt Comments
Acts as a calcium sensor involved in the regulatory pathway for the control of intracellular Na+ and K+ homeostasis and salt tolerance. Binding of a CBL protein to the regulatory NAF domain of a CIPK serine-threonine protein kinase lead to the activation of the kinase in a calcium-dependent manner. Operates in synergy with CIPK24/SOS2 to activate the plasma membrane Na+/H+ antiporter SOS1. Involved in salt stress responses by mediating calcium-dependent microfilament reorganization. The CBL4/CIPK6 complex mediates translocation of AKT2 from the endoplasmic reticulum to the plasma membrane. Both myristoylation and S-acylation are required for AKT2 activation.

For research use only, not for clinical use.