NCBI Accession #
NP_566902.1
NCBI GenBank Nucleotide #
NM_114697.4
NCBI Official Full Name
BTB and TAZ domain protein 2
NCBI Official Synonym Symbols
ATBT2; BTB and TAZ domain protein 2
NCBI Protein Information
BTB and TAZ domain protein 2
NCBI Summary
encodes a protein (BT2) that is an essential component of the TAC1-mediated telomerase activation pathway. Acts redundantly with BT3 and BT1 during female gametophyte development and with BT3 during male gametophyte development. BT2 also mediates multiple responses to nutrients, stresses, and hormones.
UniProt Protein Name
BTB/POZ and TAZ domain-containing protein 2
UniProt Synonym Protein Names
BTB and TAZ domain protein 2
UniProt Primary Accession #
Q94BN0
UniProt Secondary Accession #
Q9STL6
UniProt Related Accession #
Q94BN0
UniProt Comments
May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Plays a key role as a component of the TAC1-mediated telomerase activation pathway certainly by targeting a telomerase repressor to degradation. Seems to occupy an integral position in a complex signaling network that perceives, integrates, and responds to multiple, and sometimes competing, signals. Enhances responses to auxin in postgermination and vegetative development. Also negatively regulates ABA- and sugar-mediated inhibition of the germination. Essential for female and male gametophyte development.