BoNT-A | Botulinum toxin A

Inquiry

Cat: PA01915

Size: 0,5 mg

Host: Rabbit

Clonality: Polyclonal

Confirmed reactivity: Botulinum toxin A heavy chain

Datasheet:

Product Info

Immunogen

Recombinat C-terminal heavy chain of BoNT/A1, residues 876–1296, which is cloned into a pET28a His-tag vector (Novagen) and overexpressed in E.coli. UniProt: https://www.uniprot.org/uniprot/P10845

Host

Rabbit

Clonality

Polyclonal

Purity

Total IgG. Protein G purified in PBS pH 7.4.

Format

Lyophilized

Reconstitution

For reconstitution add 250 µl, of sterile water

Storage

Lyophilized antibody can be stored at -20°C for up to 3 years. Re-constituted antibody can be stored at 4°C for several days to weeks. Once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.

Application

ELISA (ELISA)

Recommended dilution

To be determined by end user

Reactivity

Confirmed reactivity

Botulinum toxin A heavy chain

Not reactive in

No confirmed exceptions from predicted reactivity are currently known

Description

Botulinum toxin is a toxin produced by bacteria of the anaerobic gram-positive clostridium genus (Clostridium botulinum, Clostridium butyricum, Clostridium barra, and Clostridium argentinae). These strains are widely distributed and can be found in soil and dust. There are eight types of botulinum toxin, called A-H types. Types A and B are capable of causing disease in humans (botulism) and are longest active in the body, and are also used commercially (botulism) and in medicine. The C-G type is less common; Types E and F can cause diseases in humans, while other types can cause diseases in other animals. Bota is divided into two chains: the heavy chain and the light chain. Alternative name :Bontoxilysin-A

For research use only, not for clinical use.