Affinity purified Bauhinia lectin (BPA/BPL) (SKU: 21510028) is a tetramer lectin with a molecular weight of 120 kDa. In general, glycoconjugates containing galactose (ß-1,3) n-acetylgalactosamine structure bind best, but oligosaccharides containing α-bound n-acetylgalactosamine at the end can also bind to BPL. BPA is lactose specific and can be eluted with lactose. It is specific for blood groups A, B, O (-SA). Treating red blood cells with neuraminidase or trypsin increases agglutination, indicating that the receptor is masked by terminal carbohydrates. Makela's Group 2 sugars, especially n-acetyl-D-galactosamine, are potent inhibitors. Despite binding specificity
For research use only, not for clinical use.