NCBI Accession #
NP_182147.1
NCBI GenBank Nucleotide #
NM_130187.4
NCBI Official Full Name
BCL-2-associated athanogene 6
NCBI Official Symbol
BAG6
NCBI Official Synonym Symbols
ARABIDOPSIS THALIANA BCL-2-ASSOCIATED ATHANOGENE 6; ATBAG6; BCL-2-associated athanogene 6; T3F17.11
NCBI Protein Information
BCL-2-associated athanogene 6
NCBI Summary
A member of Arabidopsis BAG (Bcl-2-associated athanogene) proteins, plant homologs of mammalian regulators of apoptosis. Expression of BAG6 in leaves was strongly induced by heat stress. Knockout mutants exhibited enhanced susceptibility to fungal pathogen Botrytis cinerea. Plant BAG proteins are multi-functional and remarkably similar to their animal counterparts, as they regulate apoptotic-like processes ranging from pathogen attack, to abiotic stress, to plant development.
UniProt Protein Name
BAG family molecular chaperone regulator 6
UniProt Synonym Protein Names
Bcl-2-associated athanogene 6
UniProt Primary Accession #
O82345
UniProt Related Accession #
O82345
UniProt Comments
Co-chaperone that regulates diverse cellular pathways, such as programmed cell death and stress responses (PubMed:16003391). Involved in plant basal resistance (PubMed:16636050, PubMed:26739014). Involved in basal heat response through the regulation of the heat induced small HSP (sHSP) transcriptional cascade (PubMed:26580143).