NCBI Accession #
NP_194748.1
NCBI GenBank Nucleotide #
NM_119165.4
NCBI Official Full Name
H[+]-ATPase 2
NCBI Official Synonym Symbols
AHA2; F9N11.40; F9N11_40; H(+)-ATPase 2; P-TYPE H(+)-ATPASE ISOFORM 2; PLASMA MEMBRANE PROTON ATPASE 2; PMA2
NCBI Protein Information
H[+]-ATPase 2
NCBI Summary
belongs to the P-type ATPase superfamily of cation-transporting ATPases, pumps protons out of the cell, generating a proton gradient that drives the active transport of nutrients by proton symport. has two autoinhibitory regions within the C-terminal dom
UniProt Protein Name
ATPase 2, plasma membrane-type
UniProt Synonym Protein Names
Proton pump 2
UniProt Primary Accession #
P19456
UniProt Related Accession #
P19456
UniProt Comments
The plasma membrane H+ ATPase of plants and fungi generates a proton gradient that drives the active transport of nutrients by H+-symport (PubMed:10748244, PubMed:12920605, PubMed:27013734). The resulting external acidification and/or internal alkinization may mediate growth responses (PubMed:10748244, PubMed:12920605). Involved in maintaining the membrane potential and delta-pH, together forming the plasma membrane protonmotive force (PMF) required for root and hypocotyl elongation and root tropism (PubMed:22214817, PubMed:24492258). Important for root growth and development during different nitrogen regimes (PubMed:25382626). Forms a functional cation-translocating unit with CNGC17 that is activated by PSKR1/BAK1 and possibly other BAK1/RLK complexes (PubMed:26071421).