ATP-dependent helicase BRM (BRM), Recombinant Protein
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ATP-dependent helicase BRM (BRM), Recombinant Protein

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Cat: RP00100
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana ATP-dependent helicase BRM (BRM) , partial
Product Gene Name
BRM recombinant protein
Product Synonym Gene Name
BRM
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
245,439 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
ATP-dependent helicase

NCBI/Uniprot Data

NCBI Accession #
NP_001318432.1
NCBI GI #
1063703449
NCBI GenBank Nucleotide #
NM_001337166.1
NCBI GeneID
819210
NCBI Official Full Name
transcription regulatory protein SNF2
NCBI Official Symbol
BRM
NCBI Official Synonym Symbols
ARABIDOPSIS THALIANA BRAHMA; ATBRM; BRAHMA; CHA2; CHR2; CHROMATIN REMODELING 2; T3F17.33
NCBI Protein Information
transcription regulatory protein SNF2
NCBI Summary
Encodes a SWI/SNF chromatin remodeling ATPase that upregulates transcription of all three CUC genes and is involved in the formation and/or maintenance of boundary cells during embryogenesis. Also mediates repression of expression of seed storage proteins in vegetative tissues. Interacts strongly with AtSWI3C, also with AtSWI3B, but not with AtSWI3A or AtSWI3D.
UniProt Gene Name
BRM
UniProt Synonym Gene Names
AtCHR2
UniProt Protein Name
ATP-dependent helicase BRM
UniProt Synonym Protein Names
Protein BRAHMA
UniProt Primary Accession #
Q6EVK6
UniProt Secondary Accession #
O82366; O82780
UniProt Related Accession #
Q6EVK6
UniProt Comments
ATPase subunit of a multiprotein complex equivalent of the SWI/SNF complex that acts by remodeling the chromatin by catalyzing an ATP-dependent alteration in the structure of nucleosomal DNA. Represses embryonic genes in leaves and controls shoot development and flowering. Activates flower homeotic genes. The association of BRM with its target genes requires REF6 (PubMed:27111034). Necessary to acquire heat stress (HS) memory, by globally binding to HS memory genes (PubMed:27680998).

For research use only, not for clinical use.