NCBI Accession #
XP_015620598.1
NCBI GenBank Nucleotide #
XM_015765112.1
NCBI Official Full Name
ATP-citrate synthase alpha chain protein 3
NCBI Official Symbol
LOC4352549
NCBI Official Synonym Symbols
ACLA-3
NCBI Protein Information
ATP-citrate synthase alpha chain protein 3
UniProt Synonym Gene Names
ATP-citrate synthase A-3
UniProt Protein Name
ATP-citrate synthase alpha chain protein 3
UniProt Synonym Protein Names
ATP-citrate lyase A-3; Citrate cleavage enzyme A-3
UniProt Primary Accession #
Q2QNG7
UniProt Secondary Accession #
A0A0P0YBE8
UniProt Related Accession #
Q2QNG7
UniProt Comments
ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA, used for the elongation of fatty acids and biosynthesis of isoprenoids, flavonoids and malonated derivatives. May supply substrate to the cytosolic acetyl-CoA carboxylase, which generates the malonyl-CoA used for the synthesis of a multitude of compounds, including very long chain fatty acids and flavonoids. In contrast to all known animal ACL enzymes having a homomeric structure, plant ACLs are composed of alpha and beta chains .