Artocarpus integrifolia Lectin (AIA) - TRITC (Rhodamine)
Description
A tetramer double chain structure composed of 4 identical propolymers is obtained by affinity chromatography with an isoelectric pH of 7.8. The lectin is specific to blood type O (+SA) and t. Jacalin is considered a galactose-specific lectin that can be eluted with galactose or glycodisaccharide. Jacalin's post-translational proteolytic modification gives lectin a new carbohydrate binding site involving the N end of the α-chain. The structure of this protein explains its carbohydrate-binding specificity to the t antigen disaccharide Galβ1,3 galnac. Effective inhibitors of jacalin include D-galactose, β-Met-Gal, and 2-deoxy-α-D-galactose. AIA is labeled with tetramethyl Rhodamine isothiocyanate (TRITC) and combined with the appropriate amount of fluorescent dye to provide the best staining properties of this lectin. TRITC is a bright orange or red fluorescent dye whose excitation is well suited to the 532nm laser line. Tritc-labeled AIA can be used for cell imaging applications. This product is a stable liquid.
Product Info
For research use only, not for clinical use.