Artocarpus integrifolia Lectin (AIA) - Separopore® 6B SuperTrap™ Cartridge

Jacalin agglutinin (AIA) is a tetramer double-stranded structure consisting of four identical propolymers with an isoelectric pH of 7.8. The lectin is specific to blood type O (+SA) and t. Jacalin is considered a galactose-specific lectin that can be eluted with galactose or glycodisaccharide. The proteolytic modification after Jacalin translation gives the lectin a new carbohydrate binding site involving the N end of the I ±- chain. The structure of this protein explains its glycobinding specificity for the T-antigen disaccharide GalI ²1,3 galnac. Effective inhibitors of jacalin include D-galactose, I ²-Met-Gal, and 2-deoxy-I ± d-galactose. The crosslinked 6B SeparoporeA ® is properly coupled to the Artocarpus integrfolia lectin (AIA), providing a fast-flowing cartridge that can capture the affinity-bound material and retain it during washing, then elute the affinity-purified material.