Artocarpus integrifolia Lectin (AIA) - HRP (Horseradish Peroxidase)
Description
A tetramer double chain structure composed of 4 identical propolymers is obtained by affinity chromatography with an isoelectric pH of 7.8. The lectin is specific to blood type O (+SA) and t. Jacalin is considered a galactose-specific lectin that can be eluted with galactose or glycodisaccharide. Jacalin's post-translational proteolytic modification gives lectin a new carbohydrate binding site involving the N end of the α-chain. The structure of this protein explains its carbohydrate binding specificity for the t antigen disaccharide galß 1,3galnac. Effective inhibitors of jacalin include D-galactose, ß-Met-Gal and 2-deoxy-α-d-galactose. Horseradish peroxidase (HRP) is a 40 kDa protein that catalyzes substrate oxidation by hydrogen peroxide to produce colored or fluorescent products or release light as a byproduct of the reaction. It is most commonly used in western blotting, immunoassays, and immunohistochemical methods.
Product Info
For research use only, not for clinical use.