Artocarpus integrifolia Lectin (AIA) - Cy3
Description
A tetramer double chain structure composed of 4 identical propolymers is obtained by affinity chromatography with an isoelectric pH of 7.8. The lectin is specific to blood type O (+SA) and t. Jacalin is considered a galactose-specific lectin that can be eluted with galactose or glycodisaccharide. Jacalin's post-translational proteolytic modification gives lectin a new carbohydrate binding site involving the N end of the α-chain. The structure of this protein explains its carbohydrate binding specificity for the t antigen disaccharide galß 1,3galnac. Effective inhibitors of jacalin include D-galactose, ß-Met-Gal and 2-deoxy-α-d-galactose. Cy3 can show the binding pattern of tree lectin in cell imaging and flow cytometry. Cy3 is more light resistant than many other fluorophores and can be seen with TRITC filter groups. It is often used in combination with green fluorescent dyes for double labeling.
Product Info
For research use only, not for clinical use.