ARP8 | Actin-related protein 8, (clone 13F10,A4,G6), N-Terminal

Antibody is recognizing following epitope, amino acids 2-26:  aa 2-ILKKVWG SVWNRSNSGKDLVNHQRA-26 This antibody is recognizing the full-length 52 kDa recombinant ARP8 protein expressed in Escherichia coli as well as endogenous ARP8 of identical molecular weight in Arabidopsis thaliana extracts from different tissues: all vegetative and reproductive organs examined including seedlings, roots and siliques, with higher concentrations of the protein detected in  developing flower buds and flowers within the inflorescence.

Actin-associated proteins (ARPs) are present in the nucleus of all eukaryotic cells, but their function is generally only understood in the context of their presence in yeast and animal chromatin modification complexes. The amino acid homology of Arabidopsis ARP8 with yeast actin and Arabidopsis ACT2 is 30% and 29%, respectively. Because it is not closely related to yeast or human ARP8, and has similar weak homology to yeast ARP8 and ARP9, Arabidopsis ARP8 is considered to be plant-specific orphan ARP.