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Arginine decarboxylase 2 (SPE2), Recombinant Protein
Cat: RP02019
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana Arginine decarboxylase 2 (SPE2) , partial
Product Gene Name
SPE2 recombinant protein
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
77,219 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Arginine decarboxylase
NCBI/Uniprot Data
NCBI Accession #
NP_195197.1
NCBI GI #
15236176
NCBI GenBank Nucleotide #
NM_119637.3
NCBI GeneID
829623
NCBI Official Full Name
arginine decarboxylase 2
NCBI Official Symbol
ADC2
NCBI Official Synonym Symbols
ARGININE DECARBOXYLASE; arginine decarboxylase 2; ATADC2; SPE2; T4L20.290; T4L20_290
NCBI Protein Information
arginine decarboxylase 2
NCBI Summary
encodes a arginine decarboxylase (ADC), a rate-limiting enzyme that catalyzes the first step of polyamine (PA) biosynthesis via ADC pathway in Arabidopsis thaliana. Arabidopsis genome has two ADC paralogs, ADC1 and ADC2. ADC2 is stress-inducible (osmotic stress). Double mutant analysis showed that ADC genes are essential for the production of PA, and are required for normal seed development. Overexpression causes phenotypes similar to GA-deficient plants and these plants show reduced levels of GA due to lower expression levels of AtGA20ox1, AtGA3ox3 and AtGA3ox1.
UniProt Gene Name
ADC2
UniProt Synonym Gene Names
ADC 2Curated; ARGDC 2Curated; AtADC2
UniProt Protein Name
Arginine decarboxylase 2
UniProt Synonym Protein Names
ADC-NCurated
UniProt Primary Accession #
O23141
UniProt Secondary Accession #
Q8H165; Q93ZG4
UniProt Related Accession #
O23141
UniProt Comments
Required for the biosynthesis of putrescine. Catalyzes the first step of polyamine (PA) biosynthesis to produce putrescine from arginine (PubMed:14684170, PubMed:15733873, PubMed:16045477, PubMed:25409942). Is a major contributor to basal arginine decarboxylase (ADC) activity and putrescine biosynthesis (PubMed:25409942). Accumulation of putrescine plays a positive role in salt stress tolerance (PubMed:14684170). Accumulation of putrescine plays a positive role in freezing tolerance (PubMed:18701673). Production of PA is essential for normal seed development (PubMed:15733873). Controls PA homeostasis which is crucial for normal plant growth and development (PubMed:27014322).
For research use only, not for clinical use.