NCBI Accession #
NP_181221.1
NCBI GenBank Nucleotide #
NM_129238.3
NCBI Official Full Name
aquaporin TIP1-1
NCBI Official Symbol
GAMMA-TIP
NCBI Official Synonym Symbols
gamma tonoplast intrinsic protein; GAMMA TONOPLAST INTRINSIC PROTEIN 1; GAMMA-TIP; GAMMA-TIP1; GAMMA-TONOPLAST INTRINSIC PROTEIN; T1J8.1; T1J8_1; TIP1;1; TONOPLAST INTRINSIC PROTEIN 1;1
NCBI Protein Information
aquaporin TIP1-1
NCBI Summary
Encodes a tonoplast intrinsic protein, which functions as water channel. It has also been shown to be able to facilitate the transport of urea and hydrogen peroxide. Highly expressed in vascular tissues of the root, stem, cauline leaves and flowers but not in the apical meristems.
UniProt Synonym Gene Names
AQP.1; Gamma-TIP; AtTIP1;1
UniProt Protein Name
Aquaporin TIP1-1
UniProt Synonym Protein Names
Aquaporin TIP; Gamma-tonoplast intrinsic protein; Gamma-TIP; Tonoplast intrinsic protein 1-1; AtTIP1;1; Tonoplast intrinsic protein, root-specific RB7
UniProt Entry Name
TIP11_ARATH
UniProt Primary Accession #
P25818
UniProt Secondary Accession #
P21652; Q42075; Q8L5T8
UniProt Related Accession #
S22202
UniProt Comments
Function: Water channel required to facilitate the transport of water, diffusion of amino acids and/or peptides from the vacuolar compartment to the cytoplasm. Does not promote glycerol permeability. May play a role in the control of cell turgor and cell expansion. Its function is impaired by Hg2+. May be involved in a vesicle-based metabolite routing through or between pre-vacuolar compartments and the central vacuole. Transports urea in yeast cells in a pH-independent manner. Transports H2O2 in yeast cells.0346Subunit structure: Interacts with cucumber mosaic virus (CMV) Protein 1a.5Subcellular location: Vacuole membrane; Multi-pass membrane protein. Note: Tonoplast. Specifically located in the tonoplast of lytic or degradative vacuoles (LV) By similarity.4Tissue specificity: In all the vegetative organs, but not in seeds. Preferentially expressed in roots.1Induction: By gibberellins.Domain: Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).Disruption phenotype: Plants display lesion formation or plant death, and low contents of glucose, fructose, inositol, and threonic, succinic, fumaric, and malic acids.4Sequence similarities: Belongs to the MIP/aquaporin (TC 1.A.8) family. TIP (TC 1.A.8.10) subfamily. Sequence caution: The sequence CAA38633.1 differs from that shown. Reason: Frameshift at position 244.