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Aquaporin PIP2-1 (PIP2-1) (PIP2A), Recombinant Protein
Cat: RP00077
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana Aquaporin PIP2-1 (PIP2-1)
Product Synonym Names
Recombinant Aquaporin PIP2-1 (PIP2-1); Aquaporin PIP2-1; Plasma membrane intrinsic protein 2-1; AtPIP2;1 Plasma membrane intrinsic protein 2a; PIP2a
Product Gene Name
PIP2A recombinant protein
Product Synonym Gene Name
PIP2-1; PIP2A
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
AKDVEAVPGE GFQTRDYQDP PPAPFIDGAE LKKWSFYRAV IAEFVATLLF LYITVLTVIG YKIQSDTDAG GVDCGGVGIL GIAWAFGGMI FILVYCTAGI SGGHINPAVT FGLFLARKVS LPRALLYIIA QCLGAICGVG FVKAFQSSYY TRYGGGANSL ADGYSTGTGL AAEIIGTFVL VYTVFSATDP KRSARDSHVP VLAPLPIGFA VFMVHLATIP ITGTGINPAR SFGAAVIYNK SKPWDDHWIF WVGPFIGAAI AAFYHQFVLR ASGSKSLGSF RSAANV
Sequence Positions
2-287
Chromosome Location
Chromosome: 3; NC_003074.8 (19803655..19805713, complement). Location: chromosome: 3
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
30,474 Da
Storage
Store at -20℃. For extended storage, store at -20 or -80℃.
NCBI/Uniprot Data
NCBI Accession #
NP_001030851.1
NCBI GI #
79314872
NCBI GenBank Nucleotide #
NM_001035774.1
NCBI GeneID
824510
NCBI Official Full Name
aquaporin PIP2-1
NCBI Official Symbol
PIP2A
NCBI Official Synonym Symbols
PIP2; PIP2;1; PIP2A; PLASMA MEMBRANE INTRINSIC PROTEIN 2; PLASMA MEMBRANE INTRINSIC PROTEIN 2;1; plasma membrane intrinsic protein 2A
NCBI Protein Information
aquaporin PIP2-1
NCBI Summary
a member of the plasma membrane intrinsic protein subfamily PIP2. localizes to the plasma membrane and exhibits water transport activity in Xenopus oocyte. expressed specifically in the vascular bundles and protein level increases slightly during leaf dev. When expressed in yeast cells can conduct hydrogen peroxide into those cells.
UniProt Gene Name
PIP2-1
UniProt Synonym Gene Names
PIP2A; AtPIP2;1; PIP2a
UniProt Protein Name
Aquaporin PIP2-1
UniProt Synonym Protein Names
Plasma membrane intrinsic protein 2-1; AtPIP2;1; Plasma membrane intrinsic protein 2a
UniProt Entry Name
PIP21_ARATH
UniProt Primary Accession #
P43286
UniProt Related Accession #
S44084
UniProt Comments
Function: Water channel required to facilitate the transport of water across cell membrane. Probably involved in root water uptake. Its function is impaired by Hg2+.Subcellular location: Cell membrane; Multi-pass membrane protein. Note: A fuzzy intracellular localization is induced by salt (NaCl) treatment.1Tissue specificity: Predominantly expressed in roots and green siliques. Also expressed at lower level above ground and in flower buds.Domain: Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).Post-translational modification: Ubiquitinated by RMA1, leading to proteasomal degradation.2The phosphorylation at Ser-280 and Ser-283 is altered by salt (NaCl) and hydrogen peroxide H2O2 treatments. Phosphorylation of Ser-283 is required for plasma membrane targeting.Sequence similarities: Belongs to the MIP/aquaporin (TC 1.A.8) family. PIP (TC 1.A.8.11) subfamily.
For research use only, not for clinical use.