NCBI Accession #
NP_196834.3
NCBI GenBank Nucleotide #
NM_121333.4
NCBI Official Full Name
ARF GTPase-activating protein
NCBI Official Synonym Symbols
AGD3; ARF-GAP DOMAIN3; ASCULAR NETWORK DEFECTIVE 3; SCARFACE; T31B5.120; T31B5_120; VAN3
NCBI Protein Information
ARF GTPase-activating protein
NCBI Summary
Belongs to 15-member small GTPase gene family, ARF-GAP domain proteins (AGD); corresponds to AGD3, and is one of four proteins belonging to class 1, together with AGD1, AGD2 and AGD4. The protein contains four domains: BAR domain, PH domain, an ARF-GAP domain, and two Ankyrin repeats. In sfc mutants, the secondary and tertiary veins of cotyledons, leaves, sepals and petals are largely replaced by small segments of discontinuous veins. sfc mutants have exaggerated responses to auxin.
UniProt Synonym Gene Names
; ARF GAP AGD3; AtAGD3
UniProt Protein Name
ADP-ribosylation factor GTPase-activating protein AGD3
UniProt Synonym Protein Names
Protein ARF-GAP DOMAIN 3; AtAGD3; Protein FORKED 2
UniProt Primary Accession #
Q5W7F2
UniProt Secondary Accession #
Q0WNK6; Q9LYU6
UniProt Related Accession #
Q5W7F2
UniProt Comments
GTPase-activating protein (GAP) for ADP ribosylation factor (ARF). Involved in the spatial control of provascular differentiation. Required for the formation of the normal pattern of continuous secondary veins. Involved in auxin signaling but not in polar auxin transport or in auxin responses. Required for PIN1 internalization in roots.