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Actin-related protein 6 (ARP6), Recombinant Protein
Cat: RP01082
Size: 0.02 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (E-Coli)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 0.1 mg (Baculovirus)/ 1 mg (E-Coli)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Yeast)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana Actin-related protein 6 (ARP6)
Product Gene Name
ARP6 recombinant protein
Product Synonym Gene Name
ARP6
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
MSNIVVLDNG GGLIKAGQGG ERDPTTVIPN CLYKPLSSKK FIHPSPLTTL SDEIDLTSAA VRRPIDRGYL INSDLQREIW SHLFTSLLHI APSSSSLLLT EAPLSIPSVQ RTTDELVFED FGFSSLYIAH PQSLVHLYEA SRQPDSILSK TQCSLVVDCG FSFTHAVPVL HNFTLNHAIK RIDLGGKAFT NYLKELVSYR SINVMDETFL VDDAKEKLCF VSLDLLRDLR LARNGNTLIK STYVLPDGVT HTKGYVKDPQ AAKRFLSLSE KESVVVMDKV GERKKADMNK NEIDLTNERF LVPETLFQPA DLGMNQAGLA ECIVRAINSC HSYLQPVLYQ SIILTGGSTL FPQLKERLEG ELRPLVPDHF DVKITTQEDP ILGVWRGGSL LASSPDFESM CVTKAEYEEL GSARCRRRFF H
Sequence Positions
1-421, Full length protein
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
46,944 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Actin-like protein
NCBI/Uniprot Data
NCBI Accession #
NP_566861.1
NCBI GI #
18406999
NCBI GenBank Nucleotide #
NM_114070.4
NCBI GeneID
823150
NCBI Official Full Name
actin-related protein 6
NCBI Official Symbol
ARP6
NCBI Official Synonym Symbols
actin-related protein 6; ATARP6; EARLY IN SHORT DAYS 1; ESD1; SUF3; SUPPRESSOR OF FRI 3
NCBI Protein Information
actin-related protein 6
NCBI Summary
Encodes ACTIN-RELATED PROTEIN6 (ARP6), a putative component of a chromatin-remodeling complex. Required for both histone acetylation and methylation of the FLC chromatin in Arabidopsis. Along with PIE1 forms a complex to deposit modified histone H2A.Z at several loci within the genome. This modification alters the expression of the target genes (i.e. FLC, MAF4, MAF6). Incorporation of this variant histone into chromatin mediates the ambient temperature response. Located at specific regions of the nuclear periphery. Expression throughout plants shown by in-situ and immunolocalization methods. Mutants show defects in fertility, leaf, flower and inflorescence development and shorter flowering times. ARP6 also is involved in globally controlling developmental responses to ambient temperature through incorporation of variant histone H2A.Z into chromatin.
UniProt Gene Name
ARP6
UniProt Synonym Gene Names
ESD1; SUF3
UniProt Protein Name
Actin-related protein 6
UniProt Synonym Protein Names
Protein EARLY IN SHORT DAYS 1; Protein SUPPRESSOR OF FRIGIDA 3
UniProt Primary Accession #
Q8LGE3
UniProt Secondary Accession #
Q8GZL0; Q8GZL1; Q8GZL2; Q8GZL3; Q8GZL4; Q8GZL5; Q8GZL6; Q8GZL7; Q8GZL8; Q8GZL9; Q8GZM0
UniProt Related Accession #
Q8LGE3
UniProt Comments
Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant H2A.F/Z leading to transcriptional regulation of selected genes (e.g. FLC) by chromatin remodeling. Binds to the promoter region of FLC chromatin. Required for the activation of FLC and FLC/MAF genes expression to levels that inhibit flowering, through both histone H3 and H4 acetylation and methylation mechanisms. Involved in several developmental processes including organization of plant organs, leaves formation, flowering time repression, and fertility. Modulates photoperiod-dependent epidermal leaves cell development; promotes cell division in long days, and cell expansion/division in short days. May be involved in the regulation of pathogenesis-related proteins (PRs).
For research use only, not for clinical use.