NCBI Accession #
NP_567763.2
NCBI GenBank Nucleotide #
NM_118831.4
NCBI Official Full Name
aconitase 2
NCBI Official Symbol
ACO2
NCBI Official Synonym Symbols
aconitase 2; F10M23.310; F10M23_310
NCBI Protein Information
aconitase 2
NCBI Summary
Encodes an aconitase that can catalyze the conversion of citrate to isocitrate through a cis-aconitate intermediate, indicating that it may participate in the TCA cycle and other primary metabolic pathways. The protein is believed to accumulate in the mitochondria and the cytosol. It affects CSD2 (At2g28190 - a superoxide dismutase) transcript levels and may play a role in the response to oxidative stress. One member of the family (ACO1 - At35830) was shown to specifically bind to the 5' UTR of CSD2 in vitro.
UniProt Synonym Gene Names
mACO2
UniProt Protein Name
Aconitate hydratase 2, mitochondrial
UniProt Synonym Protein Names
Citrate hydro-lyase 2
UniProt Primary Accession #
Q94A28
UniProt Secondary Accession #
Q9SZ36
UniProt Related Accession #
Q94A28
UniProt Comments
Catalyzes the isomerization of citrate to isocitrate via cis-aconitate. Contributes to oxidative stress tolerance (PubMed:17013749). Involved in acetate assimilation (PubMed:25061985).