NCBI Accession #
NP_195308.1
NCBI GenBank Nucleotide #
NM_119749.4
NCBI Official Full Name
aconitase 1
NCBI Official Symbol
ACO1
NCBI Official Synonym Symbols
aconitase 1; F4B14.100; F4B14_100
NCBI Protein Information
aconitase 1
NCBI Summary
Encodes an aconitase that can catalyze the conversion of citrate to isocitrate through a cis-aconitate intermediate, indicating that it may participate in the TCA cycle and other primary metabolic pathways. The protein is believed to accumulate in the mitochondria and the cytosol. It affects CSD2 (At2g28190 - a superoxide dismutase) transcript levels and may play a role in the response to oxidative stress. This enzyme can also specifically bind to the 5' UTR of CSD2 in vitro.
UniProt Synonym Gene Names
Aconitase 1
UniProt Protein Name
Aconitate hydratase 1
UniProt Synonym Protein Names
Citrate hydro-lyase 1
UniProt Primary Accession #
Q42560
UniProt Secondary Accession #
Q9SZT1
UniProt Related Accession #
Q42560
UniProt Comments
Catalyzes the isomerization of citrate to isocitrate via cis-aconitate. Contributes to oxidative stress tolerance (PubMed:17013749). May have a role in respiration (PubMed:25061985).