NCBI Accession #
NP_200128.1
NCBI GenBank Nucleotide #
NM_124695.4
NCBI Official Full Name
regulatory components of ABA receptor 3
NCBI Official Symbol
RCAR3
NCBI Official Synonym Symbols
MFH8.10; MFH8_10; PYL8; PYR1-like 8; regulatory components of ABA receptor 3
NCBI Protein Information
regulatory components of ABA receptor 3
NCBI Summary
Encodes RCAR3, a regulatory component of ABA receptor. Interacts with protein phosphatase 2Cs ABI1 and ABI2. Stimulates ABA signaling.
UniProt Synonym Gene Names
ABIP1; RCAR3
UniProt Protein Name
Abscisic acid receptor PYL8
UniProt Synonym Protein Names
ABI1-binding protein 1; PYR1-like protein 8; Regulatory components of ABA receptor 3
UniProt Primary Accession #
Q9FGM1
UniProt Secondary Accession #
Q0WRI3
UniProt Related Accession #
Q9FGM1
UniProt Comments
Receptor for abscisic acid (ABA) required for ABA-mediated responses such as stomatal closure and germination inhibition. Inhibits the activity of group-A protein phosphatases type 2C (PP2Cs) in an ABA-independent manner but more efficiently when activated by ABA. Confers enhanced sensitivity to ABA (PubMed:19407143, PubMed:19624469, PubMed:19769575, PubMed:19889877, PubMed:23844015, PubMed:21658606). Can be activated by both (-)-ABA and (+)-ABA (PubMed:23844015). Mediates crosstalk between ABA and auxin signaling to regulate lateral root growth. Required for lateral root growth suppression by ABA. In response to auxin, promotes lateral root growth by enhancing MYB77-dependent transcription of the auxin-responsive gene IAA19. Enhances the abilities of MYB44 and MYB73 to activate IAA19 gene (PubMed:24894996).