NCBI Accession #
NP_196163.1
NCBI GenBank Nucleotide #
NM_120626.3
NCBI Official Full Name
Polyketide cyclase/dehydrase and lipid transport superfamily protein
NCBI Official Symbol
PYL5
NCBI Official Synonym Symbols
AtPYL5; K18I23.25; K18I23_25; PYRABACTIN RESISTANCE 1-LIKE 5; RCAR8; regulatory component of ABA receptor 8
NCBI Protein Information
Polyketide cyclase/dehydrase and lipid transport superfamily protein
NCBI Summary
Encodes a member of the PYR (pyrabactin resistance)/PYL(PYR1-like)/RCAR (regulatory components of ABA receptor) family proteins with 14 members. PYR/PYL/RCAR family proteins function as abscisic acid sensors. Mediate ABA-dependent regulation of protein phosphatase 2Cs ABI1 and ABI2.
UniProt Synonym Gene Names
ABIP3; RCAR8
UniProt Protein Name
Abscisic acid receptor PYL5
UniProt Synonym Protein Names
ABI1-binding protein 3; PYR1-like protein 5; Regulatory components of ABA receptor 8
UniProt Primary Accession #
Q9FLB1
UniProt Related Accession #
Q9FLB1
UniProt Comments
Receptor for abscisic acid (ABA) required for ABA-mediated responses such as stomatal closure and germination inhibition. Inhibits the activity of group-A protein phosphatases type 2C (PP2Cs) in an ABA-independent manner but more efficiently when activated by ABA. Confers enhanced sensitivity to ABA (PubMed:19407143, PubMed:19624469, PubMed:23844015, PubMed:21658606). Can be activated by both (-)-ABA and (+)-ABA (PubMed:23844015).