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Abscisic acid 8'-hydroxylase 2 (CYP707A2), Recombinant Protein
Cat: RP00078
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana Abscisic acid 8'-hydroxylase 2 (CYP707A2)
Product Synonym Names
Recombinant Abscisic acid 8'-hydroxylase 2 (CYP707A2); Abscisic acid 8'-hydroxylase 2; ABA 8'-hydroxylase 2 EC= 1.14.13.93; Cytochrome P450 707A2
Product Gene Name
CYP707A2 recombinant protein
Product Synonym Gene Name
CYP707A2
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
MQISSSSSSN FFSSLYADEP ALITLTIVVV VVVLLFKWWL HWKEQRLRLP PGSMGLPYIG ETLRLYTENP NSFFATRQNK YGDIFKTHIL GCPCVMISSP EAARMVLVSK AHLFKPTYPP SKERMIGPEA LFFHQGPYHS TLKRLVQSSF MPSALRPTVS HIELLVLQTL SSWTSQKSIN TLEYMKRYAF DVAIMSAFGD KEEPTTIDVI KLLYQRLERG YNSMPLDLPG TLFHKSMKAR IELSEELRKV IEKRRENGRE EGGLLGVLLG AKDQKRNGLS DSQIADNIIG VIFAATDTTA SVLTWLLKYL HDHPNLLQEV SREQFSIRQK IKKENRRISW EDTRKMPLTT RVIQETLRAA SVLSFTFREA VQDVEYDGYL IPKGWKVLPL FRRIHHSSEF FPDPEKFDPS RFEVAPKPYT YMPFGNGVHS CPGSELAKLE MLILLHHLTT SFRWEVIGDE EGIQYGPFPV PKKGLPIRVT PI
Sequence Positions
1-482
Chromosome Location
Chromosome: 2; NC_003071.7 (12494851..12499723, complement). Location: chromosome: 2
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
55,176 Da
Storage
Store at -20℃. For extended storage, store at -20 or -80℃.
Protein Family
Abscisic acid 8'-hydroxylase
NCBI/Uniprot Data
NCBI Accession #
NP_001189629.1
NCBI GI #
334184553
NCBI GenBank Nucleotide #
NM_001202700.1
NCBI GeneID
817457
NCBI Official Full Name
abscisic acid 8'-hydroxylase 2
NCBI Official Symbol
CYP707A2
NCBI Official Synonym Symbols
cytochrome P450; family 707; polypeptide 2; subfamily A; T9I4.17; T9I4_17
NCBI Protein Information
abscisic acid 8'-hydroxylase 2
NCBI Summary
Encodes a protein with ABA 8'-hydroxylase activity, involved in ABA catabolism. Member of the CYP707A gene family. This gene predominantly accumulates in dry seeds and is up-regulated immediately following imbibition. CYP707A2 appears to play a major role in the rapid decrease in ABA levels during early seed imbibition.
UniProt Gene Name
CYP707A2
UniProt Synonym Gene Names
ABA 8'-hydroxylase 2
UniProt Protein Name
Abscisic acid 8'-hydroxylase 2
UniProt Synonym Protein Names
Cytochrome P450 707A2
UniProt Entry Name
ABAH2_ARATH
UniProt Primary Accession #
O81077
UniProt Related Accession #
T02739
UniProt Comments
Function: Involved in the oxidative degradation of abscisic acid, but not in the isomerization of the produced 8'-hydroxyabscisic acid (8'-OH-ABA) to (-)-phaseic acid (PA). Involved in the control of seed dormancy and germination.Catalytic activity: +-abscisate + NADPH + O2 = 8'-hydroxyabscisate + NADP+ + H2O.Cofactor: Heme group By similarity.Pathway: Plant hormone degradation; abscisic acid degradation.Subcellular location: Membrane; Single-pass membrane protein Potential. Tissue specificity: Mainly expressed in dry seeds. Lower expression in rosette leaves, flowers, siliques and stems. Not expressed in roots. Expressed in both endosperm and vascular tissues of embryo during the seed development and in cortex and endodermis in germinating embryo.Developmental stage: Up-regulated from late-maturation to mature dry seed. Up-regulated immediately after seed imbibition, reaching a maximum at 6 hours and decreasing therafter.Induction: By abscisic acid, dehydration and rehydration. Expression regulated by phytochrome B.Disruption phenotype: Plants show a hyperdormancy phenotype.Sequence similarities: Belongs to the cytochrome P450 family.
For research use only, not for clinical use.