NCBI Accession #
NP_195210.2
NCBI GenBank Nucleotide #
NM_119650.4
NCBI Official Full Name
Phosphorylase superfamily protein
NCBI Official Symbol
AT4G34840
NCBI Official Synonym Symbols
ARABIDOPSIS METHYLTHIOADENOSINE NUCLEOSIDASE 2; ATMTAN2; ATMTN2; F11I11.80; F11I11_80; methylthioadenosine nucleosidase 2; METHYLTHIOADENOSINE NUCLEOSIDASE 2; MTAN2; MTN2
NCBI Protein Information
Phosphorylase superfamily protein
NCBI Summary
Encodes one of the 5'-methylthioadenosine nucleosidases (AT4G38800/MTN1; AT4G34840/MTN2). Double mutant, mtn1-1mtn2-1, retains approximately 14% of the MTN enzyme activity present in the wild type and displays a pleiotropic phenotype that includes altered vasculature and impaired fertility.
UniProt Synonym Gene Names
MTAN2; AtMTN2; MTA nucleosidase; AtMTAN2; AdoHcy nucleosidase; SAH nucleosidase; SRH nucleosidase
UniProt Protein Name
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 2
UniProt Synonym Protein Names
5'-methylthioadenosine nucleosidase; MTA nucleosidase; MTA/SAH nucleosidase 2; AtMTAN2; S-adenosylhomocysteine nucleosidase; AdoHcy nucleosidase; SAH nucleosidase; SRH nucleosidase
UniProt Primary Accession #
Q7XA67
UniProt Secondary Accession #
Q9SW50
UniProt Related Accession #
Q7XA67
UniProt Comments
Enzyme of the methionine cycle that catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Contributes to the maintenance of AdoMet homeostasis and is required to sustain high rates of ethylene synthesis.