NCBI Accession #
NP_195591.1
NCBI GenBank Nucleotide #
NM_120040.4
NCBI Official Full Name
methylthioadenosine nucleosidase 1
NCBI Official Symbol
MTN1
NCBI Official Synonym Symbols
ARABIDOPSIS METHYLTHIOADENOSINE NUCLEOSIDASE 1; ATMTAN1; ATMTN1; methylthioadenosine nucleosidase 1; METHYLTHIOADENOSINE NUCLEOSIDASE 1; MTAN1; T9A14.80; T9A14_80
NCBI Protein Information
methylthioadenosine nucleosidase 1
NCBI Summary
Encodes one of the 5'-methylthioadenosine nucleosidases (AT4G38800/MTN1; AT4G34840/MTN2). Double mutant, mtn1-1mtn2-1, retains approximately 14% of the MTN enzyme activity present in the wild type and displays a pleiotropic phenotype that includes altered vasculature and impaired fertility.
UniProt Synonym Gene Names
MTAN; MTAN1; AtMTN1; MTA nucleosidase; AtMTAN1; AdoHcy nucleosidase; SAH nucleosidase; SRH nucleosidase
UniProt Protein Name
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 1
UniProt Synonym Protein Names
5'-methylthioadenosine nucleosidase; MTA nucleosidase; MTA/SAH nucleosidase 1; AtMTAN1; S-adenosylhomocysteine nucleosidase; AdoHcy nucleosidase; SAH nucleosidase; SRH nucleosidase
UniProt Primary Accession #
Q9T0I8
UniProt Comments
Enzyme of the methionine cycle that catalyzes the irreversible cleavage of the glycosidic bond in 5'-methylthioadenosine (MTA) to adenine and 5'-methylthioribose. Contributes to the maintenance of AdoMet homeostasis and is required to sustain high rates of ethylene synthesis. Inactive towards S-adenosylhomocysteine (SAH/AdoHcy).