NCBI Accession #
NP_001078599.1
NCBI GenBank Nucleotide #
NM_001085130.2
NCBI Official Full Name
Cobalamin-independent synthase family protein
NCBI Official Symbol
ATMS1
NCBI Official Synonym Symbols
ATCIMS; ATMETS; COBALAMIN-INDEPENDENT METHIONINE SYNTHASE; methionine synthesis 1; MPI7.60; MPI7_60
NCBI Protein Information
Cobalamin-independent synthase family protein
NCBI Summary
Encodes a cytosolic cobalamin-independent methionine synthase, involved in methionine regeneration via the activated methyl cycle (SAM cycle). The protein undergoes thiolation following treatment with the oxidant tert-butylhydroperoxide.
UniProt Synonym Gene Names
CIMS; AtMS1
UniProt Protein Name
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 1
UniProt Synonym Protein Names
Cobalamin-independent methionine synthase 1; AtMS1; Vitamin-B12-independent methionine synthase 1
UniProt Primary Accession #
O50008
UniProt Secondary Accession #
Q6KCR2; Q8H162; Q93ZK3
UniProt Related Accession #
O50008
UniProt Comments
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.