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5'-3' exoribonuclease 4 (XRN4), Recombinant Protein
Cat: RP01166
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana 5'-3' exoribonuclease 4 (XRN4) , partial
Product Gene Name
XRN4 recombinant protein
Product Synonym Gene Name
XRN4
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
107,778 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
5'-3' exoribonuclease
NCBI/Uniprot Data
NCBI Accession #
NP_175851.1
NCBI GI #
15221841
NCBI GenBank Nucleotide #
NM_104327.4
NCBI GeneID
841891
NCBI Official Full Name
exoribonuclease 4
NCBI Official Symbol
XRN4
NCBI Official Synonym Symbols
5'-3' EXORIBONUCLEASE; ACC INSENSITIVE 1; AIN1; ATXRN4; EIN5; ETHYLENE INSENSITIVE 5; exoribonuclease 4; EXORIBONUCLEASE 4; F20D21.30; F20D21_30
NCBI Protein Information
exoribonuclease 4
NCBI Summary
Involved in the ethylene response. XRN4 does not appear to regulate ethylene signaling via an RNA-INDUCED SILENCING COMPLEX-based RNA silencing mechanism but acts by independent means. Endogenous suppressor of posttranscriptional gene silencing.
UniProt Gene Name
XRN4
UniProt Synonym Gene Names
AIN1; EIN5
UniProt Protein Name
5'-3' exoribonuclease 4
UniProt Synonym Protein Names
Protein ACC INSENSITIVE 1; Protein ETHYLENE INSENSITIVE 5; Protein EXORIBONUCLEASE 4
UniProt Primary Accession #
Q9FQ04
UniProt Secondary Accession #
Q9SLI5
UniProt Related Accession #
Q9FQ04
UniProt Comments
Possesses 5'->3' exoribonuclease activity. Acts as an endogenous post-transcriptional gene silencing (PTGS) suppressor. Degrades miRNA target cleavage products that lack a 5'-cap structure. Antagonizes the negative feedback regulation on EIN3 by promoting EBF1 and EBF2 mRNA decay, which consequently allows the accumulation of EIN3 protein to trigger the ethylene response.
For research use only, not for clinical use.