5'-3' exoribonuclease 2 (XRN2), Recombinant Protein
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5'-3' exoribonuclease 2 (XRN2), Recombinant Protein

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Cat: RP01382
Size: 0.02 mg (E-Coli)/ 0.1 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 1 mg (E-Coli)/ 0.1 mg (Baculovirus)/ 1 mg (Yeast)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana 5'-3' exoribonuclease 2 (XRN2) , partial
Product Gene Name
XRN2 recombinant protein
Product Synonym Gene Name
XRN2
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
PEDIRGSEIT HQIPRLAIPK KTISLVDLKS GGLLWHEDGD KRRAPPKVIK IKRYNPEGSI SGGRLGKASH RLVLQTINAQ PDYMNINSEP ALCPNTVFQN ERVPKKIPTF KDNGIQWISP PPSQITPKKM NSPQRQKAWK KDETPQSREK SKKLKSSLKV NPLKMKKTKS PQREFTREKK KENITPQRKL TKAQRQVKHI RMMEEAKMIK QRKKEKYLRK KAKYAQGAPP KTA
Sequence Positions
780-1012. Partial
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
116,385 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.

NCBI/Uniprot Data

NCBI Accession #
NP_199069.1
NCBI GI #
15238990
NCBI GenBank Nucleotide #
NM_123619.4
NCBI GeneID
834261
NCBI Official Full Name
exoribonuclease 2
NCBI Official Symbol
XRN2
NCBI Official Synonym Symbols
AtXRN2; exoribonuclease 2; EXORIBONUCLEASE 2; K16E1.2; K16E1_2
NCBI Protein Information
exoribonuclease 2
NCBI Summary
Encodes a protein with similarity to yeast 5'-3'exonucleases and can functionally complement the yeast mutations. In Arabidopsis XRN2 acts as a suppressor of posttranscriptional gene silencing.
UniProt Gene Name
XRN2
UniProt Synonym Gene Names
AtXRN2
UniProt Protein Name
5'-3' exoribonuclease 2
UniProt Synonym Protein Names
Protein EXORIBONUCLEASE 2Curated
UniProt Primary Accession #
Q9FQ02
UniProt Secondary Accession #
Q56WR6; Q570J7; Q9AST0; Q9FH70; Q9FH71
UniProt Related Accession #
Q9FQ02
UniProt Comments
Possesses 5'->3' exoribonuclease activity (PubMed:11106401). Acts as an endogenous post-transcriptional gene silencing (PTGS) suppressor. Degrades miRNA-derived loops, excised during miRNA maturation in the nucleus (PubMed:17993620). Involved in pre-rRNA processing. Involved in the primary exonucleolytic shortening of the 5' external transcribed spacer (5'ETS), required for endonucleolytic processing at site P by the U3 snoRNP complex. Involved with XRN3 in the 5'-end processing of 5.8S and 25S rRNAs. Contributes with XRN3 to polyadenylation-dependent nuclear RNA surveillance. Involved in the degradation of aberrant polyadenylated pre-rRNA through 5'-end processing (PubMed:20338880).

For research use only, not for clinical use.