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4-coumarate--CoA ligase 4 (4CL4), Recombinant Protein
Cat: RP01475
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana 4-coumarate--CoA ligase 4 (4CL4) , partial
Product Gene Name
4CL4 recombinant protein
Product Synonym Gene Name
4CL4
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
62,559 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
NCBI/Uniprot Data
NCBI Accession #
NP_188760.3
NCBI GI #
42565074
NCBI GenBank Nucleotide #
NM_113018.4
NCBI GeneID
821677
NCBI Official Full Name
4-coumarate:CoA ligase 5
NCBI Official Symbol
4CL5
NCBI Official Synonym Symbols
4-coumarate:CoA ligase 5
NCBI Protein Information
4-coumarate:CoA ligase 5
NCBI Summary
The gene encodes a 4-coumarate coenzyme A ligase being able to use sinapate as substrate. The catalytic efficiency was in the following (descending) order: p-coumaric acid, caffeic acid, 5-OH-ferulic acid, ferulic acid and sinapic acid. At4CL5 was unable to use cinnamic acid as substrate. Knockout of At4CL5 (4cl5) revealed no effect on syringyl lignin content indicating that the activity observed does probably not occur in vivo.
UniProt Gene Name
4CL4
UniProt Synonym Gene Names
4CL 4; At4CL5
UniProt Protein Name
4-coumarate--CoA ligase 4
UniProt Synonym Protein Names
4-coumarate--CoA ligase isoform 5; At4CL5; 4-coumaroyl-CoA synthase 4
UniProt Primary Accession #
Q9LU36
UniProt Secondary Accession #
Q84P22; Q8LPN8
UniProt Related Accession #
Q9LU36
UniProt Comments
Produces CoA thioesters of a variety of hydroxy- and methoxy-substituted cinnamic acids, which are used to synthesize several phenylpropanoid-derived compounds, including anthocyanins, flavonoids, isoflavonoids, coumarins, lignin, suberin and wall-bound phenolics.
For research use only, not for clinical use.