NCBI Accession #
NP_001185400.1
NCBI GenBank Nucleotide #
NM_001198471.1
NCBI Official Full Name
fatty acid biosynthesis 1
NCBI Official Symbol
FAB1
NCBI Official Synonym Symbols
ARABIDOPSIS BETA-KETOACYL-ACP SYNTHETASE 2; ATKAS2; BETA-KETOACYL-ACP SYNTHETASE 2; F25A4.7; F25A4_7; fatty acid biosynthesis 1; KAS2
NCBI Protein Information
fatty acid biosynthesis 1
NCBI Summary
Encodes a plastidic beta-ketoacyl-ACP synthase II, involved in fatty acid elongation from 16:0-ACP to 18:0-ACP. Homozygous knock-out mutants are embryo lethal, indicating early embryo development is sensitive to elevated 16:0.
UniProt Synonym Gene Names
FAB1; AtKAS2; Beta-ketoacyl-ACP synthetase 2
UniProt Protein Name
3-oxoacyl-[acyl-carrier-protein] synthase II, chloroplastic
UniProt Synonym Protein Names
Beta-ketoacyl-acyl-carrier-protein synthase II; AtKAS2; Beta-ketoacyl-ACP synthetase 2; Protein FATTY ACID BIOSYNTHESIS 1
UniProt Primary Accession #
Q9C9P4
UniProt Secondary Accession #
Q8RXF5; Q945N5; Q9SSG8
UniProt Related Accession #
Q9C9P4
UniProt Comments
Essential protein that catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Specific for elongation from C-16 and C-16 to unsaturated C-18 fatty acids. Confers resistance to low temperatures by maintaining chloroplast membranes integrity. Involved in the regulation of fatty acids ratios during seed metabolism. Required for embryo development, especially at the transition from the globular to the heart stage.