3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGR), Recombinant Protein
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3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGR), Recombinant Protein

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Cat: RP10129
Species: Zea mays (Maize)
Datasheet:

Product Info

Full Product Name
Recombinant Zea mays 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGR)
Product Synonym Names
Recombinant 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGR); 3-hydroxy-3-methylglutaryl-coenzyme A reductase; HMG-CoA reductase EC= 1.1.1.34
Product Gene Name
HMGR recombinant protein
Product Synonym Gene Name
HMGR
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
MEVRGGVGQG SAARHPPAPE PSRAAARVQA GDALPLPIRH TNLIFSALFA ASLAYLMRRW REKIRSSTPL HAVGLAEMLA IFGLVASLIY LLSFFGIAFV QSIVSSGDDD EDFLVGSGSS GSAAAPSRQH AQAPAPCELL GSPAAAPEKM PEDDEEIVAS VVAGKVPSYA LEARLGDCRR AAGIRREALR RITGRDIEGL PLDGFDYASI LGQCCELPVG YVQLPVGVAG PLLLDGRRFY LPMATTEGCL VASTNRGCKA IAESGGATSV VLRDAMTRAP VARFPTARRA AELKAFLEDP ANFDTLSVVF NRSSRFARLQ GVQCAMAGRN LYMRFSCSTG DAMGMNMVSK GVQNVLDFLQ DDFHDMDVIS ISGNFCSDKK PSAVNWIEGR GKSVVCEAVI GEEVVKKVLK TDVQSLVELN TIKNLAGSAV AGALGGFNAH ASNIVTAIFI ATGQDPAQNV ESSHCITMLE PVNAGRDLHI SVTMPSIEVG TVGGGTQLAS QSACLDLLGV RGASRDRPGS NARLLATVVA GGVLAGELSL LSALAAGQLV KSHMKYNRSS KDVSSTTATE KTRQREVDV
Sequence Positions
1-579
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
60,931 Da
Storage
Store at -20℃. For extended storage, store at -20 or -80℃.

NCBI/Uniprot Data

NCBI Accession #
O24594.1
NCBI GI #
11132778
NCBI Official Full Name
3-hydroxy-3-methylglutaryl-coenzyme A reductase
UniProt Gene Name
HMGR
UniProt Synonym Gene Names
HMG-CoA reductase
UniProt Protein Name
3-hydroxy-3-methylglutaryl-coenzyme A reductase
UniProt Entry Name
HMDH_MAIZE
UniProt Primary Accession #
O24594
UniProt Comments
Function: Catalyzes the synthesis of mevalonate. The specific precursor of all isoprenoid compounds present in plants.Catalytic activity: (R)-mevalonate + CoA + 2 NADP+ = (S)-3-hydroxy-3-methylglutaryl-CoA + 2 NADPH.Pathway: Metabolic intermediate biosynthesis; (R)-mevalonate biosynthesis; (R)-mevalonate from acetyl-CoA: step 3/3.Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein. Sequence similarities: Belongs to the HMG-CoA reductase family.

For research use only, not for clinical use.