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3-hydroxy-3-methylglutaryl-coenzyme A reductase 2 (HMG2), Recombinant Protein
Cat: RP14957
Species: Solanum lycopersicum (Tomato) (Lycopersicon esculentum)
Datasheet:
Product Info
Full Product Name
Recombinant Solanum lycopersicum 3-hydroxy-3-methylglutaryl-coenzyme A reductase 2 (HMG2)
Product Synonym Names
Recombinant 3-hydroxy-3-methylglutaryl-coenzyme A reductase 2 (HMG2); 3-hydroxy-3-methylglutaryl-coenzyme A reductase 2; HMG-CoA reductase 2 EC= 1.1.1.34
Product Gene Name
HMG2 recombinant protein
Product Synonym Gene Name
HMG2
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
MDVRRRSEEP VYPSKVFAAD EKPLKPHKKQ QQQQEDKNTL LIDASDALPL PLYLTTNGLF FTMFFSVMYF LLSRWREKIR NSTPLHVVTL SELGAIVSLI ASVIYLLGFF GIGFVQTFVS RGNNDSWDEN DEEFLLKEDS RCGPATTLGC AVPAPPARQI APMAPPQPSM SMVEKPAPLI TSASSGEDEE IIKSVVQGKI PSYSLESKLG DCKRAASIRK EVMQRITGKS LEGLPLEGFN YESILGQCCE MPIGYVQIPV GIAGPLLLNG KEFSVPMATT EGCLVASTNR GCKAIYASGG ATCILLRDGM TRAPCVRFGT AKRAAELKFF VEDPIKFESL ANVFNQSSRF ARLQRIQCAI AGKNLYMRLC CSTGDAMGMN MVSKGVQNVL DYLQNEYPDM DVIGISGNFC SDKKPAAVNW IEGRGKSVVC EAIITEEVVK KVLKTEVAAL VELNMLKNLT GSAMAGALGG FNAHASNIVS AVFIATGQDP AQNIESSHCI TMMEAVNDGK DLHISVTMPS IEVGTVGGGT QLASQSACLN LLGVKGANRE APGSNARLLA TVVAGSVLAG ELSLMSAISS GQLVNSHMKY NRSTKDVTKA SS
Sequence Positions
1-602
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
64,715 Da
Storage
Store at -20℃. For extended storage, store at -20 or -80℃.
Protein Family
3-hydroxy-3-methylglutaryl-coenzyme A reductase
NCBI/Uniprot Data
NCBI Accession #
P48022.1
NCBI GI #
1346298
NCBI Official Full Name
3-hydroxy-3-methylglutaryl-coenzyme A reductase 2
UniProt Gene Name
HMG2
UniProt Synonym Gene Names
HMG-CoA reductase 2
UniProt Protein Name
3-hydroxy-3-methylglutaryl-coenzyme A reductase 2
UniProt Entry Name
HMDH2_SOLLC
UniProt Primary Accession #
P48022
UniProt Secondary Accession #
O24028
UniProt Comments
Function: Catalyzes the synthesis of mevalonate. The specific precursor of all isoprenoid compounds present in plants.Catalytic activity: (R)-mevalonate + CoA + 2 NADP+ = (S)-3-hydroxy-3-methylglutaryl-CoA + 2 NADPH.Pathway: Metabolic intermediate biosynthesis; (R)-mevalonate biosynthesis; (R)-mevalonate from acetyl-CoA: step 3/3.Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein. Sequence similarities: Belongs to the HMG-CoA reductase family.
For research use only, not for clinical use.