NCBI Accession #
NP_001319413.1
NCBI GenBank Nucleotide #
NM_001334882.1
NCBI Official Full Name
Aldolase-type TIM barrel family protein
NCBI Official Symbol
AtkdsA1
NCBI Official Synonym Symbols
3-Deoxy-D-manno-octulosonate 8-phosphate synthase; KDO8PS; T8K14.8; T8K14_8
NCBI Protein Information
Aldolase-type TIM barrel family protein
NCBI Summary
Encodes a protein with 3-deoxy-8-phosphooctulonate synthase (KDOP synthase) activity which is involved in the biosynthesis of KDO, a component of cell wall rhamnogalacturonan II.
UniProt Synonym Gene Names
AtkdsA1; KDO 8-P synthase; KDOPS
UniProt Protein Name
2-dehydro-3-deoxyphosphooctonate aldolase 1
UniProt Synonym Protein Names
3-deoxy-D-manno-octulosonic acid 8-phosphate synthase; KDO-8-phosphate synthase 1; AtkdsA1; KDO 8-P synthase; KDOPS; Phospho-2-dehydro-3-deoxyoctonate aldolase
UniProt Primary Accession #
Q9AV97
UniProt Secondary Accession #
Q8L890; Q9SAJ9; B9DG45
UniProt Related Accession #
Q9AV97
UniProt Comments
Catalyzes the stereospecific condensation of D-arabinose 5-phosphate and phosphoenolpyruvate to form 3-deoxy-D-manno-octulosonate 8-phosphate (KDO-8-phosphate) and inorganic phosphate. Involved in the biosynthesis of 3-deoxy-D-manno-octulosonate (KDO) which is an indispensable component of rhamnogalacturonan II (RG-II), a structurally complex pectic polysaccharide of the primary cell wall. RG-II is essential for the cell wall integrity of rapidly growing tissues and pollen tube growth and elongation.