NCBI Accession #
NP_567344.1
NCBI GenBank Nucleotide #
NM_116969.3
NCBI Official Full Name
general regulatory factor 1
NCBI Official Symbol
GRF1
NCBI Official Synonym Symbols
general regulatory factor 1; GENERAL REGULATORY FACTOR1-G-BOX FACTOR 14-3-3 HOMOLOG ISOFORM CHI; GF14 CHI
NCBI Protein Information
general regulatory factor 1
NCBI Summary
Encodes a 14-3-3 gene, designated GRF1 chi (for general regulatory factor1-G-box factor 14-3-3 homolog isoform chi). The major native forms of 14-3-3s are homo- and hetero-dimers, the biological functions of which are to interact physically with specific client proteins and thereby effect a change in the client. As a result, 14-3-3s are involved in a vast array of processes such as the response to stress, cell-cycle control, and apoptosis, serving as adapters, activators, and repressors. There are currently 133 full-length sequences available.
UniProt Protein Name
14-3-3-like protein GF14 chi
UniProt Synonym Protein Names
General regulatory factor 1
UniProt Primary Accession #
P42643
UniProt Secondary Accession #
Q945M2; Q9M0S7
UniProt Related Accession #
P42643
UniProt Comments
Is associated with a DNA binding complex that binds to the G box, a well-characterized cis-acting DNA regulatory element found in plant genes. Involved in the regulation of nutrient metabolism (PubMed:22104211).