NCBI Accession #
NP_567443.1
NCBI GenBank Nucleotide #
NM_117556.4
NCBI Official Full Name
acireductone dioxygenase 1
NCBI Official Symbol
ARD1
NCBI Official Synonym Symbols
acireductone dioxygenase 1; ATARD1; SGB3; suppressor of G Beta 3
NCBI Protein Information
acireductone dioxygenase 1
NCBI Summary
Encodes an acireductone dioxygenase that is activated by interaction with a heterotrimeric G protein beta subunit. It is a metalloenzyme and is likely involved in the methionine salvage pathway.
UniProt Synonym Gene Names
ARD 2; Fe-ARD 2
UniProt Protein Name
1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase 2
UniProt Synonym Protein Names
Acireductone dioxygenase (Fe(2+)-requiring) 2
UniProt Primary Accession #
Q8GXE2
UniProt Secondary Accession #
O23327
UniProt Related Accession #
Q8GXE2
UniProt Comments
Catalyzes the formation of formate and 2-keto-4-methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).