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PIK-III
SPC-01707
CAS No. 1383716-40-2
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5 mg | Online Inquiry |
25 mg | Online Inquiry |
Bulk Size | Online Inquiry |
Autophagy inhibitor ; PI3K inhibitor ; LC3 inhibitor
Description |
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PIK-III (VPS34-IN2), which is a selective inhibitor of VPS34 enzymatic activity, inhibits autophagy and de novo lipidation of LC3 and leads to the stabilization of autophagy substrates. The IC50 values for VPS34 and PI(3)Kδ are 0.018 μM and 1.2 μM respectively. |
Product Details | |
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CAS No. | CAS No. 1383716-40-2 |
Description | PIK-III (VPS34-IN2), which is a selective inhibitor of VPS34 enzymatic activity, inhibits autophagy and de novo lipidation of LC3 and leads to the stabilization of autophagy substrates. The IC50 values for VPS34 and PI(3)Kδ are 0.018 μM and 1.2 μM respectively. |
Formula | C17H17N7 |
Molecular Weight | 319.36 |
Storage | 3 years -20°C powder 2 years -80°C in solvent |
Synonyms | VPS34-IN2 |
SMILES | C1CC1CC2=NC(=NC=C2C3=NC(=NC=C3)NC4=CC=NC=C4)N |
Usage | |
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Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.