PIK-III - CD BioSciences

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PIK-III

PIK-III

SPC-01707

PIK-III

CAS No. 1383716-40-2

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Autophagy inhibitor ; PI3K inhibitor ; LC3 inhibitor

Description
PIK-III (VPS34-IN2), which is a selective inhibitor of ​VPS34 enzymatic activity, inhibits autophagy and de novo lipidation of LC3 and leads to the stabilization of autophagy substrates. The IC50 values for VPS34 and PI(3)Kδ are 0.018 μM and 1.2 μM respectively.
Product Details
CAS No. CAS No. 1383716-40-2
Description PIK-III (VPS34-IN2), which is a selective inhibitor of ​VPS34 enzymatic activity, inhibits autophagy and de novo lipidation of LC3 and leads to the stabilization of autophagy substrates. The IC50 values for VPS34 and PI(3)Kδ are 0.018 μM and 1.2 μM respectively.
Formula C17H17N7
Molecular Weight 319.36
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms VPS34-IN2
SMILES C1CC1CC2=NC(=NC=C2C3=NC(=NC=C3)NC4=CC=NC=C4)N
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.