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Phospho-Jak1 (Tyr1022/Tyr1023) Antibody
SPA-06668
| Size | Price |
| 25 µg | Online Inquiry |
| 100 µg | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | Jak1 |
| Gene Abbr. | JAK1 |
| Gene ID | 3716 |
| Full Name | Janus kinase 1 |
| Alias | AIIDE, JAK1A, JAK1B, JTK3 |
| Introduction | Members of the Janus family of tyrosine kinases (Jak1, Jak2, Jak3, and Tyk2) are activated by ligands binding to a number of associated cytokine receptors. Upon cytokine receptor activation, Jak proteins become autophosphorylated and phosphorylate their associated receptors to provide multiple binding sites for signaling proteins. These associated signaling proteins, such as Stats Shc insulin receptor substrates and focal adhesion kinase (FAK) typically contain SH2 or other phospho-tyrosine-binding domains. |
| Product Details | |
|---|---|
| Host | Rabbit |
| Clonality | Polyclonal |
| Clone No. | N/A |
| Isotype | IgG |
| Immunogen | A phospho specific peptide corresponding to residues surrounding Y1022/1023 of human Jak1. |
| Usage | |
|---|---|
| Application | WB, IF |
| Dilutions | Western Blot (1:500-1:2000); Immunofluorescence (1:50-1:200) |
| MW(KDa) | 130 |
| Reactivity | Human |
| Storage & Handling | |
|---|---|
| Storage Buffer | PBS with 50% glycerol, pH 7.3. |
| Preservative | 0.02% Sodium Azide |
| Storage Temp. | Store at -20 °C. |
| Handling | Avoid freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.