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Phospho-Atg13 (Ser318) Antibody
SPA-00666
| Size | Price |
| 0.025 mg | Online Inquiry |
| 0.1 mg | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | Atg13 |
| Gene Abbr. | ATG13 |
| Gene ID | 9776 |
| Full Name | autophagy related 13 |
| Alias | KIAA0652, PARATARG8 |
| Introduction | Autophagy is a catabolic process for the autophagosomic-lysosomal degradation of bulk cytoplasmic contents. Autophagy is generally activated by conditions of nutrient deprivation but has also been associated with a number of physiological processes including development, differentiation, neurodegeneration, infection, and cancer. The molecular machinery of autophagy was largely discovered in yeast and referred to as autophagy-related (Atg) genes. Atg13 is an autophagy factor and a target of the TOR kinase signaling pathway. It is essential for autophagosome formation and mitophagy. |
| Product Details | |
|---|---|
| Host | Rabbit |
| Clonality | Polyclonal |
| Clone No. | N/A |
| Isotype | IgG |
| Immunogen | Anti-ATG13 [p Ser318] antibody was prepared by repeated immunizations with a synthetic peptide corresponding to the region near Ser318 of ATG13. |
| Usage | |
|---|---|
| Application | WB, ELISA, FC |
| Dilutions | Western Blot (1:2000); ELISA (1:25000-1:175000); Flow Cytometry (1:10-1:1000) |
| MW(KDa) | 72 |
| Reactivity | Human, Mouse |
| Validation | Knockdown Validated. |
| Specificity | This antibody is directed against the phosphorylated form of human ATG13 protein at the pS318 residue. It was cross adsorbed against the non-phosphorylated form of the immunizing peptide. Reactivity occurs against human ATG13 pS318 protein and the antibody is specific for the phosphorylated form of the protein. Reactivity with non-phosphorylated human ATG13 is minimal by ELISA and Western Blot. |
| Storage & Handling | |
|---|---|
| Storage Buffer | 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2. |
| Preservative | 0.01% Sodium Azide |
| Storage Temp. | Store at -20 °C. |
| Handling | Avoid freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.