PHA-793887 - CD BioSciences

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PHA-793887

PHA-793887

SPC-01676

PHA-793887

CAS No. 718630-59-2

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10 mM (1 mL in DMSO) Online Inquiry
5 mg Online Inquiry
50 mg Online Inquiry
200 mg Online Inquiry
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CDK inhibitor ; Apoptosis related activator

Description
PHA-793887 is a novel and potent inhibitor of CDK2, CDK5 and CDK7 with IC50 of 8 nM, 5 nM and 10 nM. It is greater than 6-fold more selective for CDK2, 5, and 7 than CDK1, 4, and 9. PHA-793887 induces cell-cycle arrest and apoptosis. Phase 1.
Product Details
CAS No. CAS No. 718630-59-2
Description PHA-793887 is a novel and potent inhibitor of CDK2, CDK5 and CDK7 with IC50 of 8 nM, 5 nM and 10 nM. It is greater than 6-fold more selective for CDK2, 5, and 7 than CDK1, 4, and 9. PHA-793887 induces cell-cycle arrest and apoptosis. Phase 1.
Formula C19H31N5O2
Molecular Weight 361.48
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms N/A
SMILES CC(C)CC(=O)NC1=NNC2=C1CN(C2(C)C)C(=O)C3CCN(CC3)C
Solubility DMSO
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.