PF-562271 - CD BioSciences

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PF-562271

PF-562271

SPC-01668

PF-562271

CAS No. 717907-75-0

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10 mM (1 mL in DMSO) Online Inquiry
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FAK inhibitor ; Pyk2 inhibitor ; CDK inhibitor

Description
PF-562271 is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM in cell-free assays, ~10-fold less potent for Pyk2 than FAK and >100-fold selectivity against other protein kinases, except for some CDKs.
Product Details
CAS No. CAS No. 717907-75-0
Description PF-562271 is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM in cell-free assays, ~10-fold less potent for Pyk2 than FAK and >100-fold selectivity against other protein kinases, except for some CDKs.
Formula C21H20F3N7O3S
Molecular Weight 507.49
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms N/A
SMILES CN(C1=C(C=CC=N1)CNC2=NC(=NC=C2C(F)(F)F)NC3=CC4=C(C=C3)NC(=O)C4)S(=O)(=O)C
Solubility DMSO
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.