Online Inquiry
PF-562271 HCl
SPC-01669
CAS No. 939791-41-0
Size | Price |
5 mg | Online Inquiry |
25 mg | Online Inquiry |
Bulk Size | Online Inquiry |
FAK inhibitor ; Pyk2 inhibitor ; CDK inhibitor
Description |
---|
PF-562271 HCl is the hydrochloride salt of PF-562271, which is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM, ~10-fold less potent for Pyk2 than FAK and >100-fold selectivity against other protein kinases, except for some CDKs. Phase 1. |
Product Details | |
---|---|
CAS No. | CAS No. 939791-41-0 |
Description | PF-562271 HCl is the hydrochloride salt of PF-562271, which is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM, ~10-fold less potent for Pyk2 than FAK and >100-fold selectivity against other protein kinases, except for some CDKs. Phase 1. |
Formula | C21H21ClF3N7O3S |
Molecular Weight | 543.95 |
Storage | 3 years -20°C powder 2 years -80°C in solvent |
Synonyms | N/A |
SMILES | CN(C1=C(C=CC=N1)CNC2=NC(=NC=C2C(F)(F)F)NC3=CC4=C(C=C3)NC(=O)C4)S(=O)(=O)C.Cl |
Usage | |
---|---|
Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.