PF-562271 HCl - CD BioSciences

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PF-562271 HCl

PF-562271 HCl

SPC-01669

PF-562271 HCl

CAS No. 939791-41-0

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FAK inhibitor ; Pyk2 inhibitor ; CDK inhibitor

Description
PF-562271 HCl is the hydrochloride salt of PF-562271, which is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM, ~10-fold less potent for Pyk2 than FAK and >100-fold selectivity against other protein kinases, except for some CDKs. Phase 1.
Product Details
CAS No. CAS No. 939791-41-0
Description PF-562271 HCl is the hydrochloride salt of PF-562271, which is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM, ~10-fold less potent for Pyk2 than FAK and >100-fold selectivity against other protein kinases, except for some CDKs. Phase 1.
Formula C21H21ClF3N7O3S
Molecular Weight 543.95
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms N/A
SMILES CN(C1=C(C=CC=N1)CNC2=NC(=NC=C2C(F)(F)F)NC3=CC4=C(C=C3)NC(=O)C4)S(=O)(=O)C.Cl
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

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