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PF-00562271 Besylate
SPC-01651
CAS No. 939791-38-5
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| 5 mg | Online Inquiry |
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FAK inhibitor ; Pyk2 inhibitor ; CDK inhibitor
| Description |
|---|
| PF-00562271 Besylate (PF-562271) is the benzenesulfonate salt of PF-562271, which is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM, ~10-fold less potent for Pyk2 than FAK and >100-fold selectivity against other protein kinases, except for some CDKs. Phase 1. |
| Product Details | |
|---|---|
| CAS No. | CAS No. 939791-38-5 |
| Description | PF-00562271 Besylate (PF-562271) is the benzenesulfonate salt of PF-562271, which is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM, ~10-fold less potent for Pyk2 than FAK and >100-fold selectivity against other protein kinases, except for some CDKs. Phase 1. |
| Formula | C21H20F3N7O3S.C6H6O3S |
| Molecular Weight | 665.66 |
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
| Synonyms | PF-562271 Besylate |
| SMILES | CN(C1=C(C=CC=N1)CNC2=NC(=NC=C2C(F)(F)F)NC3=CC4=C(C=C3)NC(=O)C4)S(=O)(=O)C.C1=CC=C(C=C1)S(=O)(=O)O |
| Usage | |
|---|---|
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.