PD184352 (CI-1040) - CD BioSciences

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PD184352 (CI-1040)

PD184352 (CI-1040)

SPC-01630

PD184352 (CI-1040)

CAS No. 212631-79-3

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MEK inhibitor ; Apoptosis related activator

Description
PD184352 (CI-1040) is an ATP non-competitive MEK1/2 inhibitor with IC50 of 17 nM in cell-based assays, 100-fold more selective for MEK1/2 than MEK5. PD184352 (CI-1040) selectively induces apoptosis. Phase 2.
Product Details
CAS No. CAS No. 212631-79-3
Description PD184352 (CI-1040) is an ATP non-competitive MEK1/2 inhibitor with IC50 of 17 nM in cell-based assays, 100-fold more selective for MEK1/2 than MEK5. PD184352 (CI-1040) selectively induces apoptosis. Phase 2.
Formula C17H14ClF2IN2O2
Molecular Weight 478.67
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms N/A
SMILES C1CC1CONC(=O)C2=C(C(=C(C=C2)F)F)NC3=C(C=C(C=C3)I)Cl
Solubility DMSO
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.