PCI-34051 - CD BioSciences

service-banner

PCI-34051

PCI-34051

SPC-01620

PCI-34051

CAS No. 950762-95-5

Size Price
10 mM (1 mL in DMSO) Online Inquiry
10 mg Online Inquiry
100 mg Online Inquiry
Bulk Size Online Inquiry

HDAC inhibitor ; Apoptosis related activator

Description
PCI-34051 is a potent and specific HDAC8 inhibitor with IC50 of 10 nM in a cell-free assay. It has greater than 200-fold selectivity over HDAC1 and 6, more than 1000-fold selectivity over HDAC2, 3, and 10. PCI-34051 induces caspase-dependent apoptosis.
Product Details
CAS No. CAS No. 950762-95-5
Description PCI-34051 is a potent and specific HDAC8 inhibitor with IC50 of 10 nM in a cell-free assay. It has greater than 200-fold selectivity over HDAC1 and 6, more than 1000-fold selectivity over HDAC2, 3, and 10. PCI-34051 induces caspase-dependent apoptosis.
Formula C17H16N2O3
Molecular Weight 296.32
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms N/A
SMILES COC1=CC=C(C=C1)CN2C=CC3=C2C=C(C=C3)C(=O)NO
Solubility DMSO
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.