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PCI-34051
SPC-01620
CAS No. 950762-95-5
Size | Price |
10 mM (1 mL in DMSO) | Online Inquiry |
10 mg | Online Inquiry |
100 mg | Online Inquiry |
Bulk Size | Online Inquiry |
HDAC inhibitor ; Apoptosis related activator
Description |
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PCI-34051 is a potent and specific HDAC8 inhibitor with IC50 of 10 nM in a cell-free assay. It has greater than 200-fold selectivity over HDAC1 and 6, more than 1000-fold selectivity over HDAC2, 3, and 10. PCI-34051 induces caspase-dependent apoptosis. |
Product Details | |
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CAS No. | CAS No. 950762-95-5 |
Description | PCI-34051 is a potent and specific HDAC8 inhibitor with IC50 of 10 nM in a cell-free assay. It has greater than 200-fold selectivity over HDAC1 and 6, more than 1000-fold selectivity over HDAC2, 3, and 10. PCI-34051 induces caspase-dependent apoptosis. |
Formula | C17H16N2O3 |
Molecular Weight | 296.32 |
Storage | 3 years -20°C powder 2 years -80°C in solvent |
Synonyms | N/A |
SMILES | COC1=CC=C(C=C1)CN2C=CC3=C2C=C(C=C3)C(=O)NO |
Solubility | DMSO |
Usage | |
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Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.