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Pazopanib
SPC-01618
CAS No. 444731-52-6
| Size | Price |
| 25 mg | Online Inquiry |
| 100 mg | Online Inquiry |
| Bulk Size | Online Inquiry |
VEGFR inhibitor ; c-Kit inhibitor ; PDGFR inhibitor ; FGFR inhibitor ; CSF-1R inhibitor ; Cysteine Protease activator ; Autophagy activator
| Description |
|---|
| Pazopanib (GW786034) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit and c-Fms/CSF1R with IC50 of 10 nM, 30 nM, 47 nM, 84 nM, 74 nM, 140 nM and 146 nM in cell-free assays, respectively. Pazopanib induces cathepsin B activation and autophagy. |
| Product Details | |
|---|---|
| CAS No. | CAS No. 444731-52-6 |
| Description | Pazopanib (GW786034) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit and c-Fms/CSF1R with IC50 of 10 nM, 30 nM, 47 nM, 84 nM, 74 nM, 140 nM and 146 nM in cell-free assays, respectively. Pazopanib induces cathepsin B activation and autophagy. |
| Formula | C21H23N7O2S |
| Molecular Weight | 437.52 |
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
| Synonyms | GW786034 |
| SMILES | CC1=C(C=C(C=C1)NC2=NC=CC(=N2)N(C)C3=CC4=NN(C(=C4C=C3)C)C)S(=O)(=O)N |
| Usage | |
|---|---|
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.