Paxalisib (GDC-0084) - CD BioSciences

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Paxalisib (GDC-0084)

Paxalisib (GDC-0084)

SPC-01617

Paxalisib (GDC-0084)

CAS No. 1382979-44-3

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PI3K inhibitor ; mTOR inhibitor

Description
Paxalisib (GDC-0084, RG7666) is a brain penetrant inhibitor of PI3K and mTOR with Kiapp values of 2 nM, 46 nM, 3 nM, 10 nM and 70 nM for PI3Kα, PI3Kβ, PI3Kδ, PI3Kγ and mTOR.
Product Details
CAS No. CAS No. 1382979-44-3
Description Paxalisib (GDC-0084, RG7666) is a brain penetrant inhibitor of PI3K and mTOR with Kiapp values of 2 nM, 46 nM, 3 nM, 10 nM and 70 nM for PI3Kα, PI3Kβ, PI3Kδ, PI3Kγ and mTOR.
Formula C18H22N8O2
Molecular Weight 382.42
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms RG7666
SMILES CC1(C2=NC3=C(N2CCO1)N=C(N=C3N4CCOCC4)C5=CN=C(N=C5)N)C
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

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