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PARP2 Knockout Cell Line
SPL-02451
| Size | Price |
| 1 Unit | Online Inquiry |
| Description |
|---|
| 17p deletion |
| Target Information | |
|---|---|
| Target Name | PARP2 |
| Gene Abbr. | PARP2 |
| Gene ID | 10038 |
| Full Name | poly(ADP-ribose) polymerase 2 |
| Alias | ADPRT2, ADPRTL2, ADPRTL3, ARTD2, PARP-2 |
| Species | Human |
| Genomic Locus | chr14:20343651 |
| Introduction | This gene encodes poly(ADP-ribosyl)transferase-like 2 protein, which contains a catalytic domain and is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. The basic residues within the N-terminal region of this protein may bear potential DNA-binding properties, and may be involved in the nuclear and/or nucleolar targeting of the protein. Two alternatively spliced transcript variants encoding distinct isoforms have been found. [provided by RefSeq, Jul 2008]. |
| Product Details | |
|---|---|
| Cell Line Model | HAP1 |
| Genotype | PARP2 17bp deletion knockout |
| Description | 17p deletion |
| Parental Cell Line | C631 |
| Cell Number | 1x10^6 |
| Handling Specifications | |
|---|---|
| Culture Medium | IMDM + 10% FBS |
| Disclaimer | This product is classified under IATA regulations as a GMMO (genetically modified micro-organism) and will ship as UN3245. If applicable, ensure facility meets all requirements per local and country regulations. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.