Pamapimod - CD BioSciences

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Pamapimod

Pamapimod

SPC-01607

Pamapimod

CAS No. 449811-01-2

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p38 MAPK inhibitor

Description
Pamapimod (R-1503, Ro4402257) is a novel, selective inhibitor of p38 mitogen-activated protein kinase. It inhibits p38α and p38β enzymatic activity with IC50 values of 0.014±0.002 and 0.48± 0.04 microM, respectively with no activity against p38delta or p38gamma isoforms.
Product Details
CAS No. CAS No. 449811-01-2
Description Pamapimod (R-1503, Ro4402257) is a novel, selective inhibitor of p38 mitogen-activated protein kinase. It inhibits p38α and p38β enzymatic activity with IC50 values of 0.014±0.002 and 0.48± 0.04 microM, respectively with no activity against p38delta or p38gamma isoforms.
Formula C19H20F2N4O4
Molecular Weight 406.38
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms R-1503,Ro4402257
SMILES CN1C2=NC(=NC=C2C=C(C1=O)OC3=C(C=C(C=C3)F)F)NC(CCO)CCO
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

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